In older people, any effect of aspirin on reducing heart disease or stroke might be expected to be enhanced due to their higher underlying risk. "If you look at the new findings, at best it's neutral and at worst it increases the bleeding risk".
"It means millions of healthy older people around the world who are taking low dose aspirin without a medical reason, may be doing so unnecessarily, because the study showed no overall benefit to offset the risk of bleeding", the researchers said in a statement.
Even worse, a third study on the topic found that those who used aspirin each day had a "higher all-cause mortality" among seemingly healthy older people than those who did not take aspirin.
The participants were followed for around 4.7 years and could also not have dementia or a physical disability and had to be free of medical conditions.
"This study shows why it is so important to conduct this type of research, so that we can gain a fuller picture of aspirin's benefits and risks among healthy older persons". The new study was created to find out whether low-dose aspirin could prolong healthy, independent living in seniors who had not shown signs of heart disease.
Dr Richard Hodes, director of the National Institute on Ageing (NIA) in the U.S., said: 'Clinical guidelines note the benefits of aspirin for preventing heart attacks and strokes in persons with vascular conditions such as coronary artery disease. In the final 12 months of the trial, 62.1 percent of the participants in the aspirin group and 64.1 percent of those in the placebo group reported that they were still taking their assigned dosage.
Heart disease and stroke accounted for 19 per cent of the deaths and major bleeding for five per cent. Hemorrhagic stroke, bleeding in the brain, gastrointestinal hemorrhages or hemorrhages at other sites that required transfusion or hospitalization occurred in 361 people on aspirin and in 265 taking the placebo.
In the meantime, experts are warning against healthy people simply popping an aspirin every day and believing it will fix everything that ails them.
"ASPREE is a study that was probably long overdue", he said.
"I think it is time we started to phase out the use of aspirin broadly for the purposes of prevention in individuals who have not had a heart attack or stroke", said Michos, an associate professor of medicine and epidemiology and director of preventive cardiology at the Ciccarone Center for the Prevention of Heart Disease at the Johns Hopkins School of Medicine.
The small increase in deaths, mostly from cancer, may be coincidental and needs more study, the authors said. Numerous extra deaths were due to cancer, but Leslie Ford from the National Cancer Institute in Maryland said that until the team had analysed more data, the cancer findings "should be interpreted with caution".
For cardiovascular disease, the rate was 10.7 events per 1000 person-years in the aspirin group and 11.3 events per 1000 person-years in the placebo group - also considered no difference.
Merritt says he's not sure what really went down last Thursday when he shot Jean in his own home - but he knows she's lying. Rawlings has described Jean as a young professional and man of faith who was 'exactly the sort of citizen we want to have'.
In The New Yorker's story , Ford asked not to be identified, but told The Post she wanted to be the one to tell her story. In the Washington Post interview, the victim said that when she tried to scream, Kavanaugh put his hand over her mouth.
TMZ reports the wedding celebration is happening "soon", potentially as early as next week in the singer's home country of Canada. This comes after Hailey revealed that she has become more choosey about work in order to spend more time with Justin and family.
China will not buckle to U.S. demands in any trade negotiations, the major state-run China Daily newspaper said, while U.S. The government is also witnessing a backlash from the opposition parties over the high prices of the crude oil .
Arsenal manager Unai Emery has responded to media suggestions of a rift between himself and playmaker Mesut Ozil . New coach Unai Emery doesn't want to let him leave, though, given his form at the start of the season.
Most important among those will be genuine, intense customer obsession", he wrote on Twitter. "We're going to push through this". He said the schools would "use the same set of principles that have driven Amazon" and that "the child will be the customer".
In the meantime, major media outlets continue to credit former president Barack Obama for the economy. "Still plenty to do!" Trump often cites the tax cuts enacted by Republicans as one of the driving forces behind the economy's aggressive growth.
United Kingdom authorities blamed two former Russian agents, Andrei Lugovoi and Dmitri Kovtun, for the murder. Boshirov, who sported a goatee, denied they knew anything about Skripal or the location of his house.
In addition to them, Juan Foyth (thigh) and Moussa Sissoko (hamstring) will also miss the Premier League fixture with Liverpool. Tottenham Hotspur manager Mauricio Pochettino has forgiven Hugo Lloris .
On its Facebook page, the county said the evacuation was in effect along the Lower Little River near the Cumberland County line. In North Carolina, at least five deaths are related to the storm - but "several others are under investigation", Cooper said.
4 dead as Hurricane Florence drenches the Carolinas
Cooper cited a National Weather Service forecast that said almost the entire state could be covered in several feet of water. Officials said some 1.7 million people in the Carolinas and Virginia were warned to evacuate, but it's unclear how many did.
Florence, a wet and unwanted visitor, besieges Carolinas
Another person died from a cardiac arrest when emergency services could not reach her, due to downed trees blocking their path. North Carolina's governor, Roy Cooper, said Florence was set to cover nearly all of the state in several feet of water.
Maurizio Sarri open to have Chelsea legend back as coach
He has won everything with the club, so it's up to him. "For sure he will be a point of reference for me, for everybody here". Chelsea host promoted side Cardiff next on Saturday (3pm) at Stamford Bridge. "We need another step to be at the same level".
Del Potro: "I'm Excited To Keep Surprising Myself"
No. 1 Simona Halep retained the top spot even though she became the first No. 1 seed to lose in the first round of the U.S. This time previous year Djokovic was injured and uncertain about his future direction.